Autism is an impairing childhood neuropsychiatric disorder of which the cause is unknown. Previous research has shown strong evidence that autism is genetic in nature. In order to determine whether or not a genetic origin exists, it is imperative for investigators to study the cognitive and behavioral components of autism. This allows investigators to better identify autism subgroups and eventually narrow the focus on genetic markers (loci) underlying this condition. We believe that there may be a subgroup of autistic children with a genetic marker for language deficiency.
Phenotypic data will be collected during a related project (PI, Sigman). Infant siblings of children with autism will be evaluated developmentally at 5 time points – 6 months, 12 months, 18 months, 30 months and 42 months. During the 18-month visit, blood will be drawn for genetic screening for speech and language loci. In combination, these two studies will allow for a unique opportunity to examine language development and its relationship to the genetics of autism.
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